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Alteration of the redox balance is a key factor in HIV-1 pathogenicity, including neurotoxicity and dementia, depletion of CD4 + /CD8 + T cells, susceptibility to lung infections, and side effects of antiretroviral therapy 111

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A 2022 study involving 56 people with rheumatoid arthritis found whole-body cryotherapy significantly reduced pain compared to control groups, with lower pain levels maintained at 12-week follow-up